As shown in this featured application, Restek's Raptor Biphenyl column is ideal for developing successful LC-MS/MS pain medication screening methodologies. With its exceptionally high retention and unique selectivity, 231 multiclass drug compounds and metabolites—including over 40 isobars—can be analyzed in just 10 minutes. この注目のアプリケーションで示すように、RestekのRaptor Biphenyl は、LC-MS / MS鎮痛剤スクリーニング手法の開発に最適です。 非常に高い保持力と独自の選択性により、40以上の異性体を含む231のマルチクラス薬物化合物と代謝物をわずか10分で分析できます。
Raptor FluoroPhenyl columns can provide greater selectivity and retention for analytes that are not easily separated using a C18 column. For example, the epimeric forms of vitamin D2 and D3 25-hydroxy metabolites are important diagnostic markers for vitamin D status, but these compounds cannot be distinguished on a C18 column. The new Raptor FluoroPhenyl column provides ample chromatographic resolution for these isobaric epimers, which possess unequal bioactivities, so accurate results are generated and thus the proper diagnosis can be made.
Raptor Biphenylカラムは甲状腺ホルモンの迅速かつ高感度な分析に最適です。ここで紹介するメソッドでは、2 pg/mL (T3)または5 pg/mL (T4 and rT3)といった濃度の甲状腺ホルモンを3.5分以内に測定可能です。この分析方法は低濃度の遊離甲状腺ホルモンの臨床分析に応用できます。
Characterizing Cellular Fatty Acid Methyl Ester (FAME) Profiles to Identify Bacteria Using Gas Chromatography
Dr. Radomír Čabala, Head of the Toxicology Department at the General University Hospital in Prague, presents work on the potential utility of GC-TOFMS analysis of cellular fatty acid methyl esters (FAMEs) in identifying clinically relevant bacteria.
Raptor LC columns combine the speed of superficially porous particles (i.e., SPP or “core-shell”) with the resolution of highly selective USLC technology. Featuring Restek's most popular LC stationary phase, the rugged Raptor Biphenyl is extremely useful for fast separations in bioanalytical testing applications like drug and metabolite analyses, especially those that require a mass spectrometer (MS). (PDF - 6071kB)
Protein and particulate removal that’s fast, painless, and effective. Restek’s line of Resprep sample preparation products has expanded to include new 96-well protein precipitation (PPT) plates. Prepare serum, plasma, and other biological samples using the name you trust for quality, cleanliness, and performance. (PDF - 0kB)
Viva wide pore HPLC columns offer the largest surface area available in 250-350 Å pores, giving maximum retention and resolution of proteins, peptides, and other large biomolecules. Includes product information and chromatography for the PEGylation of oxytocin. (PDF - 0kB)